Vol. 7, Issue 2, Part A (2025)

Background: Cardiovascular risk in CKD patients cannot be addressed adequately with the conventional treatments including statin. To modify the residual risk of cardiovascular events in CKD patient, studies are conducted in determining the associations of different biomarkers with cardiovascular disease.

Objective: The aim of the present study was to evaluate the association of lipid profile and apolipoprotein-B (Apo-B) with ischemic heart disease (IHD) in CKD patients and to compare lipid profile and apolipoprotein-B (Apo-B) in CKD patient with IHD.

Materials and Methods: This cross-sectional study was carried out in the department of Nephrology and Cardiology of Chittagong Medical College Hospital from October 2019 to September 2020. 100 patients of CKD with IHD were included. IHD was diagnosed by reviewing the previous record and by doing ECG and echocardiography. Lipid Profile and Apo-B were assessed in each patient.

Results: Total cholesterol, triglycerides higher in CKD stage 4, Apo-B in stage 3 and LDL-C in stage 5 with IHD. Conclusion: Apo-B, total cholesterol, triglycerides and LDL-C were significantly high in CKD patients with IHD.