Vol. 7, Issue 2, Part A (2025)

Introduction: The objective was to describe the epidemiological and clinical profile of patients with chronic renal failure in the nephrology department of the Donka University Hospital Center.

Materials and Methods: We conducted a retrospective descriptive study in which we included all complete records of patients labeled as having chronic renal failure with a glomerular filtration rate < 15 ml/min/1.73 m2 hospitalized in the nephrology department of the Donka University Hospital.

Results: The prevalence of end-stage renal disease was 96% among these patients.

The average age was 46 years, with 113 men and 93 women, 34% housewives, 26% civil servants, and 83% married.

The main cardiovascular risk factors found were dominated by hypertension (91%), followed by gender (55%).

The top three presumed causes of CRF were chronic glomerulonephritis (40%), benign nephroaniosclerosis (28%), and diabetic nephropathy.

In terms of paraclinical findings, the average hemoglobin level was 7 g/dL, the average creatinine level was 1124 µmol/L, and the average glomerular filtration rate was 5 mL/min. Hypocalcemia was present in 80% of cases and renal atrophy in 86%.

There were 116 cases of uremic poisoning. The immediate outcome was marked by a 20% mortality rate, with a correlation between metabolic acidosis, uremic pericarditis, and death.

Conclusion: The prevalence of end-stage chronic kidney disease is significant and constantly growing, affecting young, economically active adults in our context.